Broad Spectrum Functional Activity of Structurally Related Monoanionic Au(III) Bis(Dithiolene) Complexes
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23, 2022
Yann Le Gal , Agathe Filatre-Furcate , Dominique Lorcy , Olivier Jeannin , Thierry Roisnel , Vincent Dorcet , Diana Fontinha , Denise Francisco , Miguel Prudencio , Marta Martins , Catarina Soeiro , Silvia A. Sousa , Jorge H. Leitao , Tânia S. Morais , Ines Bartolo , Nuno Taveira , Joana F. Guerreiro , Fernanda M. Marques

Are smart delivery systems the solution to overcome the lack of selectivity of current metallodrugs in cancer therapy?
DALTON TRANSACTIONS, 51, 2593-2609 2022
João Franco Machado , Tânia S. Morais

Design and Anticancer Properties of New Water-Soluble Ruthenium-Cyclopentadienyl Complexes
PHARMACEUTICALS, 15, 2022
Tânia S. Morais , Fernanda M. Marques , Paulo J. Amorim Madeira , Maria Paula Robalo , Maria Helena Garcia

Gold(I) Bis(1,2,3-triazol-5-ylidene) Complexes as Promising Selective Anticancer Compounds
JOURNAL OF MEDICINAL CHEMISTRY, 64, 15747-15757 2021
Jonas F. Schlagintweit , Christian H. G. Jakob , Nicola L. Wilke , Marie Ahrweiler , Corazon Frias , Jerico Frias , Marcel Koenig , Eva-Maria H. J. Esslinger , Fernanda M. Marques , Joao F. Machado , Robert M. Reich , Tânia S. Morais , Joao D. G. Correia , Aram Prokop , Fritz E. Kuehn

Binding of RuCp complexes with human apo-transferrin: fluorescence spectroscopy and molecular docking methods
BIOMETALS, 34, 1029-1042 2021
Filipa C. Santos , Paulo J. Costa , M. Helena Garcia , Tânia S. Morais

Emerging Molecular Receptors for the Specific-Target Delivery of Ruthenium and Gold Complexes into Cancer Cells
MOLECULES, 26, 6 2021
J. Franco Machado , Joao D. G. Correia , Tânia S. Morais

Cu(I) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action
DALTON TRANSACTIONS, 50, 1845-1865 2 2021
Diogo Sequeira , Pedro V. Baptista , Ruben Valente , M. Fatima M. Piedade , M. Helena Garcia , Tânia S. Morais , Alexandra R. Fernandes

Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6
MOLECULES, 26, 2021
Ruben D. M. Silva , João Franco Machado , Kyle Goncalves , Francisco M. Lucas , Salete Batista , R. Melo , Tânia S. Morais , Joao D. G. Correia

Bioconjugate Supramolecular Pd2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo
BIOCONJUGATE CHEMISTRY, 32, 1399-1408 2021
Ben Woods , Ruben D. M. Silva , Claudia Schmidt , Darren Wragg , Marco Cavaco , Vera Neves , Vera F. C. Ferreira , Lurdes Gano , Tânia S. Morais , Filipa Mendes , Joao D. G. Correia , Angela Casini

Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents
METALLOMICS, 12, 974-987 6 2020
Diana Fontinha , Silvia A. Sousa , Tânia S. Morais , Miguel Prudencio , Jorge H. Leitao , Yann Le Gal , Dominique Lorcy , Rafaela A. L. Silva , Mariana F. G. Velho , Dulce Belo , Manuel Almeida , Joana F. Guerreiro , Teresa Pinheiro , Fernanda Marques

Novel ruthenium cyclopentadienyl - peptide conjugate complexes against human FGFR(+) breast cancer
DALTON TRANSACTIONS, 49, 5974-5987 5 2020
J. Franco Machado , Miguel Machuqueiro , Fernanda M. Marques , M Paula Robalo , M.Fatima M.Piedade , M. Helena Garcia , Joao D. G. Correia , Tânia S. Morais

New copper(i) complexes selective for prostate cancer cells
DALTON TRANSACTIONS, 49, 12273-12286 9 2020
J. Franco Machado , Diogo Sequeira , Fernanda M. Marques , M. Fatima M. Piedade , Maria J. Villa de Brito , M. Helena Garcia , A.R. Fernandes , Tânia S. Morais

First heterobimetallic Cu(i)-dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity
NEW JOURNAL OF CHEMISTRY, 43, 12308-12317 8 2019
Catarina Bravo , M Paula Robalo , Fernanda M. Marques , Alexandra R. Fernandes , Diogo A. Sequeira , M. Fatima M. Piedade , M. Helena Garcia , Maria J. Villa de Brito , Tânia S. Morais

Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 19, 1262-1275 2019
Lurdes Gano , Teresa Pinheiro , Antonio P. Matos , Francisco Tortosa , Tiago F. Jorge , Maria S. Goncalves , Marta Martins , Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Maria H. Garcia , Fernanda M. Marques

Important cytotoxic and cytostatic effects of new copper(I)-phosphane compounds with N,N, N,O and N,S bidentate ligands
DALTON TRANSACTIONS, 47, 7819-7829 6 2018
Tânia S. Morais , Yann Jousseaume , M.Fatima M.Piedade , Catarina Roma-Rodrigues , A.R. Fernandes , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

New copper(I) and heteronuclear copper(I)-ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity
JOURNAL OF INORGANIC BIOCHEMISTRY, 169, 68-78 4 2017
Joao Lopes , David Alves , Tânia S. Morais , Paulo J. Costa , M.Fatima M.Piedade , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 17, 126-136 2017
Nuno Mendes , Francisco Tortosa , Andreia Valente , Fernanda M. Marques , Antonio Matos , Tânia S. Morais , Ana Isabel Tomaz , Fatima Gartner , M. Helena Garcia

Ruthenium new drug: paving the way for cancer therapy
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 22, S122 7 2017
Maria Helena Garcia , Andreia Valente , Tânia S. Morais , Ana Isabel Tomaz

Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds
FUTURE MEDICINAL CHEMISTRY, 8, 527-544 2016
Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Fernanda M. Marques , M. Helena Garcia

A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites
Journal of Coordination Chemistry, 68, 2923-2937 2015
Esteban Rodrígues Arce , Cynthia Sarniguet , Tânia S. Morais , Marisol Vieites , Ana Isabel Tomaz , Andrea Medeiros , Marcelo Comini , Javier Varela , Hugo Cerecetto , Mercedes Gonzalez , Fernanda Marques , M. Helena Garcia , Lucia Otero , Dinorah Gambino